TNNT1 抗体
Quick Overview for TNNT1 抗体 (ABIN7231858)
抗原
See all TNNT1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- TNNT1 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of TNNT1 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human TNNT1 protein
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- TNNT1 (Slow Skeletal Troponin T (TNNT1))
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别名
- TNNT1
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背景
- Rabbit Anti-TNNT1 Polyclonal Antibody,Troponin T, slow skeletal muscle, TnTs, Slow skeletal muscle troponin T, sTnT,TNNT1 (Troponin T1, Slow Skeletal Type) encodes a protein that is a subunit of troponin, which is a regulatory complex located on the thin filament of the sarcomere. This complex regulates striated muscle contraction in response to fluctuations in intracellular calcium concentration. This complex is composed of three subunits: troponin C, which binds calcium, troponin T, which binds tropomyosin, and troponin I, which is an inhibitory subunit. This protein is the slow skeletal troponin T subunit. Mutations in TNNT1 cause nemaline myopathy type 5, also known as Amish nemaline myopathy, a neuromuscular disorder characterized by muscle weakness and rod-shaped, or nemaline, inclusions in skeletal muscle fibers which affects infants, resulting in death due to respiratory insufficiency, usually in the second year. Multiple transcript variants encoding different isoforms have been found for TNNT1.,TNNT1
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分子量
- observerd band 30kDa
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基因ID
- 7138
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UniProt
- P13805
抗原
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