SIRP-Alpha1/beta1 (Internal Region) 抗体
The 兔 多克隆 anti-SIRP-Alpha1/beta1 antibody is suitable to detect SIRP-Alpha1/beta1 in samples from 人. It has been validated for ELISA, IHC (p) 和 WB.
产品编号 ABIN7218750
发货至:
中国
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北京 101111
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Quick Overview for SIRP-Alpha1/beta1 (Internal Region) 抗体 (ABIN7218750)
抗原
SIRP-Alpha1/beta1
适用
人
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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抗原表位
- Internal Region
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原理
- SIRP-α1/β1 Polyclonal Antibody
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特异性
- SIRP-α1/β1 Polyclonal Antibody detects endogenous levels of SIRP-α1/β1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human SIRP-alpha1/beta1
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亚型
- IgG
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anti-SIRP-Alpha1/beta1 (Internal Region) antibody
适用: 人 ELISA, IHC (p), WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- SIRP-Alpha1/beta1
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背景
- Rabbit Anti-SIRP-α1/β1 Polyclonal Antibody,SIRPA, BIT, MFR, MYD1, PTPNS1, SHPS1, SIRP, Tyrosine-protein phosphatase non-receptor type substrate 1, SHP substrate 1, SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Bit, CD172 antigen-like family member A, Inhibitory receptor SHP,The signal regulatory protein alpha encoded by SIRPA is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple alternatively spliced transcript variants have been determined for this gene.,Tyrosine-protein phosphatase non-receptor type substrate 1
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分子量
- observerd band 55kDa
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基因ID
- 140885, 10326, 100653194
抗原
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