SH3BP2 抗体 (AA 210-290)
Quick Overview for SH3BP2 抗体 (AA 210-290) (ABIN7227094)
抗原
See all SH3BP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 210-290
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原理
- 3BP2 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of 3BP2 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human 3BP2 protein at AA range: 210-290
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))
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别名
- 3BP2
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背景
- Rabbit Anti-3BP2 Polyclonal Antibody,SH3 domain-binding protein 2, 3BP-2,The protein encoded by SH3BP2 has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in SH3BP2 result in cherubism. Multiple transcript variants encoding different isoforms have been found for SH3BP2.,3BP2
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基因ID
- 6452
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UniProt
- P78314
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途径
- TCR Signaling
抗原
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