SH3BP1 抗体 (AA 170-250)
Quick Overview for SH3BP1 抗体 (AA 170-250) (ABIN7227092)
抗原
See all SH3BP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 170-250
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原理
- 3BP1 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of 3BP1 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human 3BP1 protein at AA range: 170-250
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- SH3BP1 (SH3-Domain Binding Protein 1 (SH3BP1))
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别名
- 3BP1
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背景
- Rabbit Anti-3BP1 Polyclonal Antibody,SH3 domain-binding protein 1,SH3BP1 encodes a member of the Rho GTPase activating protein (RhoGAP) family. The encoded protein regulates Rac signaling and plays a role in cytoskeletal dynamics, cell motility and epithelial junction formation. This protein's association with the exocyst complex, which tethers secretory vesicles to the plasma membrane, has been demonstrated to be important in cell motility. In a distinct complex, this protein has been shown to regulate epithelial junction formation and morphogenesis. By interacting with the Plexin-D1 cell surface receptor, this protein mediates changes in the cytoskeleton in response to semaphorin binding. This protein may promote metastasis in human liver cancer cells and tissues.,3BP1
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基因ID
- 23616
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UniProt
- Q9Y3L3
抗原
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