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SIAH1/2 抗体 (AA 160-240)

This 兔 多克隆 anti-SIAH1/2 antibody specifically detects SIAH1/2 in WB, IF, ELISA 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7217010
发货至: 中国
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Quick Overview for SIAH1/2 抗体 (AA 160-240) (ABIN7217010)

抗原

SIAH1/2 (Seven in Absentia Homolog 1/2 (SIAH1/2))

适用

  • 19
  • 18
  • 3
  • 2
  • 2
人, 小鼠, 大鼠

宿主

  • 19

克隆类型

  • 19
多克隆

标记

  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SIAH1/2 antibody is un-conjugated

应用范围

  • 19
  • 13
  • 13
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 15
    • 2
    • 2
    AA 160-240

    原理

    Siah-1/2 Polyclonal Antibody

    特异性

    Siah-1/2 Polyclonal Antibody detects endogenous levels of Siah-1/2 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human Siah-1/2 at AA range: 160-240

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    SIAH1/2 (Seven in Absentia Homolog 1/2 (SIAH1/2))

    别名

    Siah-1/2

    背景

    Rabbit Anti-Siah-1/2 Polyclonal Antibody,SIAH1, HUMSIAH, E3 ubiquitin-protein ligase SIAH1, Seven in absentia homolog 1, Siah-1, Siah-1a, SIAH2, E3 ubiquitin-protein ligase SIAH2, Seven in absentia homolog 2, Siah-2, hSiah2,SIAH1 encodes E3 ubiquitin-protein ligase SIAH1 that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.,E3 ubiquitin-protein ligase SIAH1

    分子量

    observerd band 34kDa

    基因ID

    6477, 6478
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