SESN1 抗体 (AA 240-320)
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北京 101111
Quick Overview for SESN1 抗体 (AA 240-320) (ABIN7221122)
抗原
See all SESN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 240-320
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原理
- PA26 Polyclonal Antibody
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特异性
- PA26 Polyclonal Antibody detects endogenous levels of PA26 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human PA26 at AA range: 240-320
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- SESN1 (Sestrin 1 (SESN1))
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别名
- PA26
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背景
- Rabbit Anti-PA26 Polyclonal Antibody,SESN1, PA26, SEST1, Sestrin-1, p53-regulated protein PA26,SESN1 encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The sestrin 1 mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,Sestrin-1
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分子量
- observerd band 57kDa
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基因ID
- 27244
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UniProt
- Q9Y6P5
抗原
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