Sclerostin 抗体 (AA 130-210)
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北京 101111
Quick Overview for Sclerostin 抗体 (AA 130-210) (ABIN7222960)
抗原
See all Sclerostin (SOST) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 130-210
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原理
- Rabbit Anti-Sclerostin Polyclonal Antibody
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特异性
- Sclerostin Polyclonal Antibody detects endogenous levels of Sclerostin protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from the C-terminal region of human Sclerostin at AA range: 130-210
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亚型
- IgG
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anti-Sclerostin (SOST) (AA 12-42), (N-Term) antibody
SOST 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB12388 unconjugated
anti-Sclerostin (SOST) (AA 121-180) antibodySOST 适用: 人, 小鼠, 大鼠, 兔 WB, ELISA, IF (p), ICC, IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Sclerostin (SOST) (AA 25-213) antibodySOST 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sclerostin (SOST) (AA 24-213) antibodySOST 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sclerostin (SOST) (AA 24-213) antibodySOST 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sclerostin (SOST) (AA 38-66), (N-Term) antibodySOST 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB36187 unconjugated
anti-Sclerostin (SOST) (AA 134-163) antibodySOST 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB13011 unconjugated
anti-Sclerostin (SOST) (N-Term) antibodySOST 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Sclerostin (SOST) (AA 25-209) antibodySOST 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sclerostin (SOST) (C-Term) antibodyVerified SOST 适用: 人 IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300,ELISA 1:2000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- Sclerostin (SOST)
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别名
- Sclerostin
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背景
- SOST, SclerostinSclerostin (SOST) is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in SOST are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of SOST, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.
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分子量
- 26kD
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基因ID
- 50964
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UniProt
- Q9BQB4
抗原
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