Saposin (AA 280-360) 抗体
This 兔 多克隆 antibody specifically detects Saposin in ELISA, WB 和 IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7223654
发货至:
中国
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中国
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北京 101111
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Quick Overview for Saposin (AA 280-360) 抗体 (ABIN7223654)
抗原
Saposin
适用
人
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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抗原表位
- AA 280-360
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原理
- Saposin Polyclonal Antibody
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特异性
- Saposin Polyclonal Antibody detects endogenous levels of Saposin protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human Saposin at AA range: 280-360
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亚型
- IgG
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anti-Saposin (Internal Region) antibody
适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Saposin
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背景
- Rabbit Anti-Saposin Polyclonal Antibody,PSAP, GLBA, SAP1, Proactivator polypeptide,PSAP (prosaposin) encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in PSAP have been associated with Gaucher disease and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.,Proactivator polypeptide
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分子量
- observerd band 58kDa
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基因ID
- 5660
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UniProt
- P07602
抗原
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