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RNF6 抗体 (AA 470-550)

This 兔 多克隆 antibody specifically detects RNF6 in WB 和 ELISA. It exhibits reactivity toward 人.
产品编号 ABIN7231114
发货至: 中国
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Quick Overview for RNF6 抗体 (AA 470-550) (ABIN7231114)

抗原

See all RNF6 抗体
RNF6 (RING Finger Protein 6 (RNF6))

适用

  • 45
  • 20
  • 20
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1

宿主

  • 42
  • 6

克隆类型

  • 45
  • 3
多克隆

标记

  • 25
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This RNF6 antibody is un-conjugated

应用范围

  • 41
  • 18
  • 13
  • 5
  • 4
  • 3
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 8
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 470-550

    原理

    RNF6 Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of RNF6 protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human RNF6 protein at AA range: 470-550

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    RNF6 (RING Finger Protein 6 (RNF6))

    别名

    RNF6

    背景

    Rabbit Anti-RNF6 Polyclonal Antibody,E3 ubiquitin-protein ligase RNF6, RING-type E3 ubiquitin transferase RNF6,RNF6 (Ring Finger Protein 6) is a Protein Coding gene. Diseases associated with RNF6 include Esophageal Cancer and Squamous Cell Carcinoma. Among its related pathways are Class I MHC mediated antigen processing and presentation and Androgen receptor signaling pathway. The protein encoded by RNF6 contains a RING-H2 finger motif. Deletions and mutations in RNF6 were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed.,RNF6

    分子量

    observerd band 75kDa

    基因ID

    6049

    UniProt

    Q9Y252

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Cell Size
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