RNF19A 抗体 (AA 30-110)
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Quick Overview for RNF19A 抗体 (AA 30-110) (ABIN7220922)
抗原
See all RNF19A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 30-110
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原理
- Rabbit Anti-Dorfin Polyclonal Antibody
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特异性
- Dorfin Polyclonal Antibody detects endogenous levels of Dorfin protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from the N-terminal region of human Dorfin at AA range: 30-110
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- RNF19A (Ring Finger Protein 19A (RNF19A))
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别名
- Dorfin
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背景
- RNF19A, RNF19, E3 ubiquitin-protein ligase RNF19A, Double ring-finger protein, Dorfin, RING finger protein 19A, p38RNF19A encodes a member of the ring between ring fingers (RBR) protein family, and the ring finger protein 19A, RBR E3 ubiquitin protein ligase contains two RING-finger motifs and an in between RING fingers motif. This protein is an E3 ubiquitin ligase that is localized to Lewy bodies, and ubiquitylates synphilin-1, which is an interacting protein of alpha synuclein in neurons. The encoded protein may be involved in amyotrophic lateral sclerosis and Parkinson's disease. Alternative splicing results in multiple transcript variants.
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分子量
- 90kD
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基因ID
- 25897
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UniProt
- Q9NV58
抗原
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