RNF185 抗体 (AA 121-170)
Quick Overview for RNF185 抗体 (AA 121-170) (ABIN7231102)
抗原
See all RNF185 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 121-170
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原理
- RN185 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of RN185 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human RN185 protein at AA range: 121-170
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- RNF185 (Ring Finger Protein 185 (RNF185))
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别名
- RN185
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背景
- Rabbit Anti-RN185 Polyclonal Antibody,E3 ubiquitin-protein ligase RNF185, RING finger protein 185, RING-type E3 ubiquitin transferase RNF185,RNF185 (Ring Finger Protein 185) is a Protein Coding gene. Diseases associated with RNF185 include Cystic Fibrosis. Among its related pathways are Protein processing in endoplasmic reticulum and HIV Life Cycle. GO annotations related to this gene include ligase activity. An important paralog of this gene is INPP5J. E3 ubiquitin-protein ligase that regulates selective mitochondrial autophagy by mediating Lys-63-linked polyubiquitination of BNIP1. Responsible for the cotranslational ubiquitination and degradation of CFTR in the ERAD pathway. Preferentially associates with the E2 enzymes UBE2J1 and UBE2J2.,RN185
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分子量
- observerd band 21kDa
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基因ID
- 91445
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UniProt
- Q96GF1
抗原
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