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EMP2 抗体 (AA 65-167) (Biotin)

This Biotin-conjugated 兔 多克隆 anti-EMP2 antibody specifically detects EMP2 in WB, ELISA, IHC (p) 和 IHC (fro). The antibody is reactive with 大鼠 samples.
产品编号 ABIN716578
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for EMP2 抗体 (AA 65-167) (Biotin) (ABIN716578)

抗原

EMP2 (Epithelial Membrane Protein 2 (EMP2))

适用

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大鼠

宿主

  • 39
  • 1

克隆类型

  • 39
  • 1
多克隆

标记

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This EMP2 antibody is conjugated to Biotin

应用范围

  • 28
  • 13
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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 14
    • 8
    • 4
    • 4
    • 3
    • 2
    AA 65-167

    交叉反应

    大鼠

    预测反应

    Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human EMP2

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    EMP2 (Epithelial Membrane Protein 2 (EMP2))

    别名

    EMP2

    背景

    Synonyms: EMP-2, EMP2, EMP2_HUMAN, Epithelial membrane protein 2, Protein XMP.

    Background: EMP-2 is a 167 amino acid multi-pass membrane protein that contains four-transmembrane domains and belongs to the GAS3/PMP22 (growth arrest-specific-3/peripheral myelin protein-22) family. Localized to lipid raft domains in the plasma membrane, EMP-2 regulates the expression of several target proteins and is necessary for blastocyst implantation in the uterine endometrium. Specifically, EMP-2 mediates blastocyst implantation by controlling the cell membrane expression of MHC and glycosylphosphatidylinositol-anchored proteins, as well as Integrins and caveolin-1. In adult tissues, EMP-2 is expressed in heart, lung, ovary and intestine, while fetal expression is highest in kidney, brain and liver. Overexpression of EMP-2 is associated with endometrial adenocarcinoma, suggesting a possible role for EMP-2 in tumorigenesis.

    基因ID

    2013
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