RPS6 抗体 (pSer240)
Quick Overview for RPS6 抗体 (pSer240) (ABIN7224080)
抗原
See all RPS6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer240
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原理
- Ribosomal Protein S6 (phospho Ser240) Polyclonal Antibody
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特异性
- Phospho-Ribosomal Protein S6 (S240) Polyclonal Antibody detects endogenous levels of Ribosomal Protein S6 protein only when phosphorylated at S240.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human Ribosomal Protein S6 Phospho-Ser240
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- RPS6 (Ribosomal Protein S6 (RPS6))
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别名
- Ribosomal Protein S6
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背景
- Rabbit Anti-Ribosomal Protein S6 (phospho Ser240) Polyclonal Antibody,RPS6, OK/SW-cl.2, 40S ribosomal protein S6, Phosphoprotein NP33,Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. RPS6 (ribosomal protein S6) encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of RPS6 dispersed through the genome.,40S ribosomal protein S6
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分子量
- observerd band 28kDa
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基因ID
- 6194
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UniProt
- P62753
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途径
- Carbohydrate Homeostasis, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
抗原
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