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EMP2 抗体 (AA 65-167)

This anti-EMP2 antibody is a 兔 多克隆 antibody detecting EMP2 in WB, ELISA, IF (cc), IF (p), IHC (p) 和 IHC (fro). Suitable for 大鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN716576
发货至: 中国

Quick Overview for EMP2 抗体 (AA 65-167) (ABIN716576)

抗原

EMP2 (Epithelial Membrane Protein 2 (EMP2))

适用

  • 18
  • 14
  • 10
  • 1
大鼠

宿主

  • 39

克隆类型

  • 39
多克隆

标记

  • 11
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This EMP2 antibody is un-conjugated

应用范围

  • 28
  • 13
  • 13
  • 12
  • 12
  • 7
  • 2
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 14
    • 8
    • 4
    • 4
    • 3
    • 2
    AA 65-167

    交叉反应

    大鼠

    预测反应

    Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human EMP2

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Torella, Iaconetti, Tarallo, Marino, Giurato, Veneziano, Aquila, Scalise, Mancuso, Cianflone, Valeriano, Marotta, Tammè, Vicinanza, Sasso, Cozzolino, Torella, Weisz, Indolfi: "miRNA Regulation of the Hyperproliferative Phenotype of Vascular Smooth Muscle Cells in Diabetes." in: Diabetes, Vol. 67, Issue 12, pp. 2554-2568, (2019) (PubMed).

  • 抗原

    EMP2 (Epithelial Membrane Protein 2 (EMP2))

    别名

    Emp2

    背景

    Synonyms: EMP-2, EMP2, EMP2_HUMAN, Epithelial membrane protein 2, Protein XMP.

    Background: EMP-2 is a 167 amino acid multi-pass membrane protein that contains four-transmembrane domains and belongs to the GAS3/PMP22 (growth arrest-specific-3/peripheral myelin protein-22) family. Localized to lipid raft domains in the plasma membrane, EMP-2 regulates the expression of several target proteins and is necessary for blastocyst implantation in the uterine endometrium. Specifically, EMP-2 mediates blastocyst implantation by controlling the cell membrane expression of MHC and glycosylphosphatidylinositol-anchored proteins, as well as Integrins and caveolin-1. In adult tissues, EMP-2 is expressed in heart, lung, ovary and intestine, while fetal expression is highest in kidney, brain and liver. Overexpression of EMP-2 is associated with endometrial adenocarcinoma, suggesting a possible role for EMP-2 in tumorigenesis.

    基因ID

    2013
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