RPS19 抗体 (AA 50-130)
Quick Overview for RPS19 抗体 (AA 50-130) (ABIN7224126)
抗原
See all RPS19 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 50-130
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原理
- Ribosomal Protein S19 Polyclonal Antibody
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特异性
- Ribosomal Protein S19 Polyclonal Antibody detects endogenous levels of Ribosomal Protein S19 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human Ribosomal Protein S19 at AA range: 50-130
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- RPS19 (Ribosomal Protein S19 (RPS19))
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别名
- Ribosomal Protein S19
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背景
- Rabbit Anti-Ribosomal Protein S19 Polyclonal Antibody,RPS19, 40S ribosomal protein S19,Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. RPS19 (ribosomal protein S19) encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19E family of ribosomal proteins. It is located in the cytoplasm. Mutations in RPS19 cause Diamond-Blackfan anemia (DBA), a constitutional erythroblastopenia characterized by absent or decreased erythroid precursors, in a subset of patients. This suggests a possible extra-ribosomal function for this gene in erythropoietic differentiation and proliferation, in addition to its ribosomal function. Higher expression levels of RPS19 in some primary colon carcinomas compared to matched normal colon tissues has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of RPS19 dispersed through the genome.,40S ribosomal protein S19
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分子量
- observerd band 16kDa
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基因ID
- 6223
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UniProt
- P39019
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途径
- Positive Regulation of Immune Effector Process, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
抗原
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