Rhotekin 抗体 (AA 80-160)
Quick Overview for Rhotekin 抗体 (AA 80-160) (ABIN7224140)
抗原
See all Rhotekin (RTKN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 80-160
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原理
- Rhotekin Polyclonal Antibody
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特异性
- Rhotekin Polyclonal Antibody detects endogenous levels of Rhotekin protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human Rhotekin at AA range: 80-160
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Rhotekin (RTKN)
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别名
- Rhotekin
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背景
- Rabbit Anti-Rhotekin Polyclonal Antibody,RTKN, RTKN1, Rhotekin,RTKN (rhotekin) encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.,Rhotekin
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基因ID
- 6242
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UniProt
- Q9BST9
抗原
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