ARHGEF12 抗体 (AA 420-500)
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北京 101111
Quick Overview for ARHGEF12 抗体 (AA 420-500) (ABIN7220696)
抗原
See all ARHGEF12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 420-500
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原理
- Rabbit Anti-LARG Polyclonal Antibody
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特异性
- LARG Polyclonal Antibody detects endogenous levels of LARG protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from the Internal region of human LARG at AA range: 420-500
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- ARHGEF12 (rho Guanine Nucleotide Exchange Factor (GEF) 12 (ARHGEF12))
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别名
- LARG
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背景
- ARHGEF12, KIAA0382, LARG, Rho guanine nucleotide exchange factor 12, Leukemia-associated RhoGEFRho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The Rho guanine nucleotide exchange factor 12 may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Three transcript variants encoding different isoforms have been found for this gene.
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分子量
- 173kD
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基因ID
- 23365
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UniProt
- Q9NZN5
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途径
- Neurotrophin Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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