ARHGAP24 抗体 (AA 550-630)
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Quick Overview for ARHGAP24 抗体 (AA 550-630) (ABIN7231038)
抗原
See all ARHGAP24 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 550-630
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原理
- RHG24 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of RHG24 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human RHG24 protein at AA range: 550-630
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- ARHGAP24 (rho GTPase Activating Protein 24 (ARHGAP24))
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别名
- RHG24
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背景
- Rabbit Anti-RHG24 Polyclonal Antibody,Rho GTPase-activating protein 24, Filamin-A-associated RhoGAP, FilGAP, RAC1- and CDC42-specific GTPase-activating protein of 72 kDa, RC-GAP72, Rho-type GTPase-activating protein 24, RhoGAP of 73 kDa, Sarcoma antigen NY-SAR-88, p73RhoGAP,ARHGAP24 (Rho GTPase Activating Protein 24) is a Protein Coding gene. Diseases associated with ARHGAP24 include Glomerulosclerosis, Focal Segmental, 1 and Atypical Autism. Among its related pathways are G-protein signaling_Regulation of RAC1 activity and p75 NTR receptor-mediated signalling. ARHGAP24 encodes a Rho-GTPase activating protein, which is specific for the small GTPase family member Rac. Binding of the encoded protein by filamin A targets it to sites of membrane protrusion, where it antognizes Rac. This results in suppression of lamellae formation and promotion of retraction to regulate cell polarity. Alternative splicing results in multiple transcript variants.,RHG24
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分子量
- observerd band 82kDa
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基因ID
- 83478
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UniProt
- Q8N264
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途径
- Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus
抗原
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