ARHGDIA 抗体 (pSer174)
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Quick Overview for ARHGDIA 抗体 (pSer174) (ABIN7222202)
抗原
See all ARHGDIA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer174
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原理
- Rho GDIα (phospho Ser174) Polyclonal Antibody
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特异性
- Phospho-Rho GDIα (S174) Polyclonal Antibody detects endogenous levels of Rho GDIα protein only when phosphorylated at S174.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human Rho GDIalpha Phospho-Ser174
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- ARHGDIA (rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA))
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别名
- Rho GDIalpha
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背景
- Rabbit Anti-Rho GDIα (phospho Ser174) Polyclonal Antibody,ARHGDIA, GDIA1, Rho GDP-dissociation inhibitor 1, Rho GDI 1, Rho-GDI alpha,ARHGDIA encodes a protein that plays a key role in the regulation of signaling through Rho GTPases. The encoded protein inhibits the disassociation of Rho family members from GDP (guanine diphosphate), thereby maintaining these factors in an inactive state. Activity of this protein is important in a variety of cellular processes, and expression of this gene may be altered in tumors. Mutations in this gene have been found in individuals with nephrotic syndrome, type 8. Alternate splicing results in multiple transcript variants.,Rho GDP-dissociation inhibitor 1
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分子量
- observerd band 23kDa
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基因ID
- 396
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UniProt
- P52565
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途径
- Neurotrophin Signaling Pathway
抗原
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