Retinoic Acid Receptor alpha 抗体 (pSer77)
Our Local Distributor
北京 101111
Quick Overview for Retinoic Acid Receptor alpha 抗体 (pSer77) (ABIN7223940)
抗原
See all Retinoic Acid Receptor alpha (RARA) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- pSer77
-
原理
- RARα (phospho Ser77) Polyclonal Antibody
-
特异性
- Phospho-RARα (S77) Polyclonal Antibody detects endogenous levels of RARα protein only when phosphorylated at S77.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
-
免疫原
- Synthesized peptide derived from human RARalpha Phospho-Ser77
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.
-
说明
-
Primary Antibody
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- Retinoic Acid Receptor alpha (RARA) (Retinoic Acid Receptor, alpha (RARA))
-
别名
- RARalpha
-
背景
- Rabbit Anti-RARα (phospho Ser77) Polyclonal Antibody,RARA, NR1B1, Retinoic acid receptor alpha, RAR-alpha, Nuclear receptor subfamily 1 group B member 1,RARA (retinoic acid receptor alpha)represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. RARA has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.,Retinoic acid receptor alpha
-
分子量
- observerd band 45kDa
-
基因ID
- 5914
-
UniProt
- P10276
-
途径
- Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, S100 Proteins
抗原
-