RCC1 抗体 (AA 301-350)
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北京 101111
Quick Overview for RCC1 抗体 (AA 301-350) (ABIN7226940)
抗原
See all RCC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 301-350
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原理
- RCC1 Polyclonal Antibody
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特异性
- The antibody detects endogenous RCC1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthetic peptide from human protein at AA range: 301-350
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亚型
- IgG
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anti-Regulator of Chromosome Condensation 1 (RCC1) (AA 1-240) antibody
RCC1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Regulator of Chromosome Condensation 1 (RCC1) antibodyRCC1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Regulator of Chromosome Condensation 1 (RCC1) (AA 312-421) antibodyRCC1 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal 1C1 unconjugated
anti-Regulator of Chromosome Condensation 1 (RCC1) (AA 312-421) antibodyRCC1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2F1 unconjugated
anti-Regulator of Chromosome Condensation 1 (RCC1) antibodyRCC1 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Regulator of Chromosome Condensation 1 (RCC1) (AA 1-421) antibodyRCC1 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Regulator of Chromosome Condensation 1 (RCC1) antibodyRCC1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Regulator of Chromosome Condensation 1 (RCC1) antibodyRCC1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Regulator of Chromosome Condensation 1 (RCC1) (AA 1-421) antibodyRCC1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Regulator of Chromosome Condensation 1 (RCC1) antibodyRCC1 适用: 人, 小鼠 WB 宿主: 小鼠 Monoclonal 332CT2-1-1 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:10000), ELISA (1:10000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- RCC1 (Regulator of Chromosome Condensation 1 (RCC1))
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别名
- RCC1
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背景
- Rabbit Anti-RCC1 Polyclonal Antibody,RCC1, CHC1,The Ras family small GTPase Ran is involved in nuclear envelope formation, assembly of the mitotic spindle and nuclear transport. Like other small GTPases, Ran is active in its GTP-bound form and inactive in its GDP-bound form. Nuclear RanGTP concentration is maintained through nuclear localization of guanine nucleotide exchange factor (GEF) activity, which catalyzes the exchange of bound GDP for GTP. RCC1 (regulator of chromatin condensation 1) is the only known RanGEF. RCC1 is dynamically chromatin-bound throughout the cell cycle, and this localization is required for mitosis to proceed normally. Appropriate association of RCC1 with chromatin is regulated through amino-terminal phosphorylation and methylation. RCC1 regulation of RanGTP levels in response to histone modifications regulates nuclear import during apoptosis. In mitosis RCC1 is phosphorylated at Ser11, possibly by cyclinB/cdc2. This phosphorylation may play a role in RCC1 interaction with chromatin and its RanGEF activity.,regulator of chromosome condensation 1, SNHG3-RCC1 readthrough transcript
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分子量
- observerd band 45kDa
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基因ID
- 1104
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UniProt
- P18754
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途径
- Chromatin Binding, Protein targeting to Nucleus
抗原
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