RASIP1 抗体 (AA 620-700)
Quick Overview for RASIP1 抗体 (AA 620-700) (ABIN7230920)
抗原
See all RASIP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 620-700
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原理
- RAIN Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of RAIN protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human RAIN protein at AA range: 620-700
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- RASIP1 (Ras Interacting Protein 1 (RASIP1))
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别名
- RAIN
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背景
- Rabbit Anti-RAIN Polyclonal Antibody,Ras-interacting protein 1, Rain,Required for the proper formation of vascular structures that develop via both vasculogenesis and angiogenesis. Acts as a critical and vascular-specific regulator of GTPase signaling, cell architecture, and adhesion, which is essential for endothelial cell morphogenesis and blood vessel tubulogenesis. Regulates the activity of Rho GTPases in part by recruiting ARHGAP29 and suppressing RhoA signaling and dampening ROCK and MYH9 activities in endothelial cells. May act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS-mediated transformation. Negative regulator of amino acid starvation-induced autophagy.,RAIN
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分子量
- observerd band 105kDa
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基因ID
- 54922
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UniProt
- Q5U651
抗原
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