RIN1 抗体 (AA 630-710)
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Quick Overview for RIN1 抗体 (AA 630-710) (ABIN7226044)
抗原
See all RIN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 630-710
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原理
- RIN1 Polyclonal Antibody
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特异性
- RIN1 Polyclonal Antibody detects endogenous levels of RIN1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the C-terminal region of human RIN1 at AA range: 630-710
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- RIN1 (Ras and Rab Interactor 1 (RIN1))
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别名
- RIN1
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背景
- Rabbit Anti-RIN1 Polyclonal Antibody,RIN1, Ras and Rab interactor 1, Ras inhibitor JC99, Ras interaction/interference protein 1,Ras is a membrane-associated small G protein that is indirectly coupled to receptor and nonreceptor tyrosine kinases. Ras activation is regulated by the levels of bound GTP and GDP. Several effectors of Ras have been identified, including Raf1, PI 3-kinase and RIN1. RIN1 (Ras interaction/interference) was identified as a Ras-interacting protein in yeast, and it has been shown to bind to the human H-Ras. This RIN1-Ras interaction is enhanced when Ras is bound to GTP. Unlike Raf1, RIN1 is localized primarily to the plasma membrane. RIN1 contains an SH2 domain and an amino-terminal region similar to consensus SH3 domains. RIN1 binds c-Abl and, like Raf1, interacts with 14-3-3 proteins.,Ras and Rab interactor 1
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分子量
- observerd band 84kDa
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基因ID
- 9610
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UniProt
- Q13671
抗原
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