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RAP1GAP 抗体 (AA 460-540)

This 兔 多克隆 anti-RAP1GAP antibody specifically detects RAP1GAP in WB, ELISA 和 IHC (p). The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7216788
发货至: 中国
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Quick Overview for RAP1GAP 抗体 (AA 460-540) (ABIN7216788)

抗原

See all RAP1GAP 抗体
RAP1GAP (RAP1 GTPase Activating Protein (RAP1GAP))

适用

  • 45
  • 25
  • 17
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  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
人, 小鼠

宿主

  • 35
  • 11

克隆类型

  • 26
  • 20
多克隆

标记

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  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
This RAP1GAP antibody is un-conjugated

应用范围

  • 30
  • 16
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  • 10
  • 2
  • 1
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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 460-540

    原理

    Rap1GAP Polyclonal Antibody

    特异性

    Rap1GAP Polyclonal Antibody detects endogenous levels of Rap1GAP protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the C-terminal region of human Rap1GAP at AA range: 460-540

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    RAP1GAP (RAP1 GTPase Activating Protein (RAP1GAP))

    别名

    Rap1GAP

    背景

    Rabbit Anti-Rap1GAP Polyclonal Antibody,RAP1GAP, KIAA0474, RAP1GA1, Rap1 GTPase-activating protein 1, Rap1GAP, Rap1GAP1,RAP1GAP encodes a type of GTPase-activating-protein (GAP) that down-regulates the activity of the ras-related RAP1 protein. RAP1 acts as a molecular switch by cycling between an inactive GDP-bound form and an active GTP-bound form. The product of this gene, RAP1GAP, promotes the hydrolysis of bound GTP and hence returns RAP1 to the inactive state whereas other proteins, guanine nucleotide exchange factors (GEFs), act as RAP1 activators by facilitating the conversion of RAP1 from the GDP- to the GTP-bound form. In general, ras subfamily proteins, such as RAP1, play key roles in receptor-linked signaling pathways that control cell growth and differentiation. RAP1 plays a role in diverse processes such as cell proliferation, adhesion, differentiation, and embryogenesis. Alternative splicing results in multiple transcript variants encoding distinct proteins.,Rap1 GTPase-activating protein 1

    分子量

    observerd band 73kDa

    基因ID

    5909

    UniProt

    P47736
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