RSAD2 抗体 (N-Term)
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Quick Overview for RSAD2 抗体 (N-Term) (ABIN7218578)
抗原
See all RSAD2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- RSAD2 Polyclonal Antibody
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特异性
- RSAD2 Polyclonal Antibody detects endogenous levels of RSAD2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the N-terminal region of human RSAD2
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亚型
- IgG
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anti-Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2) (AA 42-361) antibody
RSAD2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2) (AA 262-361) antibodyRSAD2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4D10 unconjugated
anti-Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2) (AA 42-361) antibodyRSAD2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2) (C-Term) antibodyRSAD2 适用: 人, 小鼠, 犬, Cow, 兔, Pig, 斑马鱼, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2) antibodyRSAD2 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 4D12 unconjugated
anti-Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2) (C-Term) antibodyRSAD2 适用: 人, 小鼠, 犬, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2) (N-Term) antibodyRSAD2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2) antibodyRSAD2 适用: 人 IF 宿主: 兔 Polyclonal unconjugated
anti-Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2) (AA 1-361) antibodyRSAD2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2) (AA 101-150) antibodyRSAD2 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠, Pig, 小鸡, Hamster WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- RSAD2 (Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2))
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别名
- RSAD2
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背景
- Rabbit Anti-RSAD2 Polyclonal Antibody,RSAD2, CIG5, Radical S-adenosyl methionine domain-containing protein 2, Cytomegalovirus-induced gene 5 protein, Viperin, Virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible,RSAD2 (Radical S-Adenosyl Methionine Domain Containing 2) is a Protein Coding gene. Diseases associated with RSAD2 include influenza and encephalitis. Among its related pathways are Immune System and Interferon gamma signaling. Gene Ontology (GO) annotations related to this gene include protein self-association and iron-sulfur cluster binding. Interferon-inducible iron-sulfur (4FE-4S) cluster-binding antiviral protein which plays a major role in the cell antiviral state induced by type I and type II interferon. Can inhibit a wide range of DNA and RNA viruses, including human cytomegalovirus (HCMV), hepatitis C virus (HCV), west Nile virus (WNV), dengue virus, sindbis virus, influenza A virus, sendai virus, vesicular stomatitis virus (VSV), and human immunodeficiency virus (HIV-1). Displays antiviral activity against influenza A virus by inhibiting the budding of the virus from the plasma membrane by disturbing the lipid rafts. This is accomplished, at least in part, through binding and inhibition of the enzyme farnesyl diphospate synthase (FPPS), which is essential for the biosynthesis of isoprenoid-derived lipids. Promotes TLR7 and TLR9-dependent production of IFN-beta production in plasmacytoid dendritic cells (pDCs) by facilitating Lys-63-linked ubiquitination of IRAK1. Plays a role in CD4+ T-cells activation and differentiation. Facilitates T-cell receptor (TCR)-mediated GATA3 activation and optimal T-helper 2 (Th2) cytokine production by modulating NFKB1 and JUNB activities. Can inhibit secretion of soluble proteins.,Radical S-adenosyl methionine domain-containing protein 2
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分子量
- observerd band 42kDa
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基因ID
- 91543
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UniProt
- Q8WXG1
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
抗原
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