RAB3IP 抗体 (AA 230-310)
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Quick Overview for RAB3IP 抗体 (AA 230-310) (ABIN7219372)
抗原
See all RAB3IP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 230-310
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原理
- RAB3IP Polyclonal Antibody
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特异性
- RAB3IP Polyclonal Antibody detects endogenous levels of RAB3IP protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human RAB3IP at AA range: 230-310
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- RAB3IP (RAB3A Interacting Protein (Rabin3) (RAB3IP))
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别名
- RAB3IP
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背景
- Rabbit Anti-RAB3IP Polyclonal Antibody,RAB3IP, RABIN8, Rab-3A-interacting protein, Rab3A-interacting protein, Rabin-3, SSX2-interacting protein,Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis.,Rab-3A-interacting protein
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分子量
- observerd band 53kDa
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基因ID
- 117177
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UniProt
- Q96QF0
抗原
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