PDHA1 抗体 (AA 290-370)
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Quick Overview for PDHA1 抗体 (AA 290-370) (ABIN7216482)
抗原
See all PDHA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 290-370
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原理
- PDHA1 Polyclonal Antibody
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特异性
- PDHA1 Polyclonal Antibody detects endogenous levels of PDHA1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the C-terminal region of human PDHA1 at AA range: 290-370
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亚型
- IgG
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anti-Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1) (AA 30-390) antibody
PDHA1 适用: 人 WB, IHC, FACS, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1) (AA 30-390) antibodyPDHA1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1) (AA 1-390) antibodyPDHA1 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1) (C-Term) antibodyPDHA1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1) antibodyKD Validated PDHA1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB3290 unconjugated Recombinant Antibody
anti-Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1) (AA 223-390) antibodyPDHA1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1) (C-Term) antibodyPDHA1 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬, 斑马鱼, 豚鼠, 兔, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1) (pSer293) antibodyPDHA1 适用: 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1) (C-Term) antibodyPDHA1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1) (pSer293) antibodyPDHA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- PDHA1 (Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1))
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别名
- PDHA1
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背景
- Rabbit Anti-PDHA1 Polyclonal Antibody,PDHA1, PHE1A, Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial, PDHE1-A type I,The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. PDHA1 encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in PDHA1 are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for PDHA1.,Pyruvate dehydrogenase E1 component subunit alpha somatic form mitochondrial
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分子量
- observerd band 43kDa
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基因ID
- 5160
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UniProt
- P08559
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途径
- Warburg Effect
抗原
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