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PC 抗体 (AA 330-410)

This anti-PC antibody is a 兔 多克隆 antibody detecting PC in WB, ELISA 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7222954
发货至: 中国

Quick Overview for PC 抗体 (AA 330-410) (ABIN7222954)

抗原

See all PC 抗体
PC (Pyruvate Carboxylase (PC))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This PC antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 5
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    AA 330-410

    原理

    PCB Polyclonal Antibody

    特异性

    PCB Polyclonal Antibody detects endogenous levels of PCB protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human PCB at AA range: 330-410

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    PC (Pyruvate Carboxylase (PC))

    别名

    PCB

    背景

    Rabbit Anti-PCB Polyclonal Antibody,PC, Pyruvate carboxylase, mitochondrial, Pyruvic carboxylase, PCB,PC encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene.,Pyruvate carboxylase mitochondrial

    分子量

    observerd band 120kDa

    基因ID

    5091

    UniProt

    P11498
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