PRC1 抗体 (pThr481)
Quick Overview for PRC1 抗体 (pThr481) (ABIN7230766)
抗原
See all PRC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pThr481
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原理
- PRC1 (Phospho-Thr481) Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of PRC1Phospho occurs at Thr481
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human PRC1 (Phospho-Thr481) Polyclonal Antibody protein at AA range: 481
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- PRC1 (Protein Regulator of Cytokinesis 1 (PRC1))
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别名
- PRC1
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背景
- Rabbit Anti-PRC1 (Phospho-Thr481) Polyclonal Antibody,Protein regulator of cytokinesis 1,PRC1 encodes a protein that is involved in cytokinesis. The protein is present at high levels during the S and G2/M phases of mitosis but its levels drop dramatically when the cell exits mitosis and enters the G1 phase. It is located in the nucleus during interphase, becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis. This protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs). It is necessary for polarizing parallel microtubules and concentrating the factors responsible for contractile ring assembly. Alternative splicing results in multiple transcript variants. PRC1 (Protein Regulator Of Cytokinesis 1) is a Protein Coding gene. Among its related pathways are Semaphorin interactions and Cytoskeletal Signaling.,PRC1
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分子量
- observerd band 72kDa
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基因ID
- 9055
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UniProt
- O43663
抗原
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