PPP1R8 抗体 (AA 170-250)
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Quick Overview for PPP1R8 抗体 (AA 170-250) (ABIN7223382)
抗原
See all PPP1R8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 170-250
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原理
- Rabbit Anti-NIPP1 Polyclonal Antibody
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特异性
- NIPP1 Polyclonal Antibody detects endogenous levels of NIPP1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from the Internal region of human NIPP1 at AA range: 170-250
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- PPP1R8 (Protein Phosphatase 1, Regulatory Subunit 8 (PPP1R8))
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别名
- NIPP1
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背景
- PPP1R8, ARD1, NIPP1, Nuclear inhibitor of protein phosphatase 1, NIPP-1, Protein phosphatase 1 regulatory inhibitor subunit 8PPP1R8 (protein phosphatase 1 regulatory subunit 8), through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by PPP1R8 are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.
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分子量
- 40kD
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基因ID
- 5511
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UniProt
- Q12972
抗原
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