PPP1R15B 抗体 (Internal Region)
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Quick Overview for PPP1R15B 抗体 (Internal Region) (ABIN7218646)
抗原
See all PPP1R15B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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原理
- PPP1R15B Polyclonal Antibody
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特异性
- PPP1R15B Polyclonal Antibody detects endogenous levels of PPP1R15B protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human PPP1R15B
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亚型
- IgG
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anti-Protein Phosphatase 1, Regulatory Subunit 15B (PPP1R15B) (Internal Region) antibody
PPP1R15B 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Regulatory Subunit 15B (PPP1R15B) (AA 480-529) antibodyPPP1R15B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Regulatory Subunit 15B (PPP1R15B) (AA 494-522), (C-Term) antibodyPPP1R15B 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB32305 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- PPP1R15B (Protein Phosphatase 1, Regulatory Subunit 15B (PPP1R15B))
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别名
- PPP1R15B
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背景
- Rabbit Anti-PPP1R15B Polyclonal Antibody,PPP1R15B, Protein phosphatase 1 regulatory subunit 15B,PPP1R15B encodes a protein phosphatase I-interacting protein that promotes the dephosphorylation of eukaryotic translation initiation factor 2A to regulate translation under conditions of cellular stress. The transcribed messenger RNA contains two upstream open reading frames (ORFs) that repress translation of the main protein coding ORF under normal conditions, while the protein coding ORF is expressed at high levels in response to stress. Continual translation of the mRNA under conditions of eukaryotic translation initiation factor 2A inactivation is thought to create a feedback loop for reactivation of the gene during recovery from stress. In addition, it has been shown that this protein plays a role in membrane traffic that is independent of translation and that it is required for exocytosis from erythroleukemia cells. Allelic variants of this gene are associated with microcephaly, short stature, and impaired glucose metabolism.,Protein phosphatase 1 regulatory subunit 15B
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分子量
- observerd band 78kDa
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基因ID
- 84919
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UniProt
- Q5SWA1
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途径
- ER-Nucleus Signaling
抗原
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