PRKAB1 抗体 (pSer182)
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北京 101111
Quick Overview for PRKAB1 抗体 (pSer182) (ABIN7212864)
抗原
See all PRKAB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer182
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原理
- AMPKβ1 (phospho Ser182) Polyclonal Antibody
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特异性
- Phospho-AMPKβ1 (S182) Polyclonal Antibody detects endogenous levels of AMPKβ1 protein only when phosphorylated at S182.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human AMPKbeta1 Phospho-Ser182
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亚型
- IgG
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anti-Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1) antibody
PRKAB1 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1) (AA 201-270) antibodyPRKAB1 适用: 小鼠, 大鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1) (pSer182) antibodyPRKAB1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1) antibodyPRKAB1 适用: 人, 小鼠 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1) (pSer181) antibodyPRKAB1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1) (AA 1-270) antibodyPRKAB1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2C3 unconjugated
anti-Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1) (AA 13-242) antibodyPRKAB1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1) (AA 1-80) antibodyPRKAB1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1) (AA 1-270) antibodyPRKAB1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3H12-1A10 unconjugated
anti-Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1) (AA 1-270) antibodyPRKAB1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D3 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- PRKAB1 (Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1))
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别名
- AMPKbeta1
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背景
- Rabbit Anti-AMPKβ1 (phospho Ser182) Polyclonal Antibody,PRKAB1, AMPK, 5'-AMP-activated protein kinase subunit beta-1, AMPK subunit beta-1, AMPKb,Protein kinase AMP-activated non-catalytic subunit beta 1encoded by PRKAB1 is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex.,5'-AMP-activated protein kinase subunit beta-1
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基因ID
- 5564
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UniProt
- Q9Y478
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途径
- AMPK Signaling, Warburg Effect
抗原
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