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PKC eta 抗体

This 兔 多克隆 anti-PKC eta antibody specifically detects PKC eta in WB 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7229318
发货至: 中国
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Quick Overview for PKC eta 抗体 (ABIN7229318)

抗原

See all PKC eta (PRKCH) 抗体
PKC eta (PRKCH) (Protein Kinase C, eta (PRKCH))

适用

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人, 小鼠, 大鼠

宿主

  • 66
  • 4

克隆类型

  • 55
  • 14
多克隆

标记

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This PKC eta antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 原理

    KPCL Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of KPCL protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human KPCL protein

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    PKC eta (PRKCH) (Protein Kinase C, eta (PRKCH))

    别名

    KPCL

    背景

    Rabbit Anti-KPCL Polyclonal Antibody,Protein kinase C eta type, PKC-L, nPKC-eta,Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. Protein Kinase C Eta encoded by PRKCH is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. It is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene. Mutations in this gene are associated with susceptibility to cerebral infarction.,KPCL

    分子量

    observerd band 75kDa

    基因ID

    5583

    UniProt

    P24723

    途径

    Myometrial Relaxation and Contraction, Thromboxane A2 Receptor Signaling
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