PKA 抗体 (AA 1-80)
This anti-PKA antibody is a 兔 多克隆 antibody detecting PKA in WB, ELISA, IHC (p) 和 IF. Suitable for 人, 小鼠 和 大鼠.
Quick Overview for PKA 抗体 (AA 1-80) (ABIN7216582)
抗原
See all PKA 抗体
PKA
(Protein Kinase A (PKA))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This PKA antibody is un-conjugated
应用范围
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
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抗原表位
- AA 1-80
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原理
- PKAα/β cat Polyclonal Antibody
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特异性
- PKAα/β cat Polyclonal Antibody detects endogenous levels of PKAα/β cat protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the N-terminal region of human PKAalpha/beta cat at AA range: 1-80
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亚型
- IgG
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anti-Protein Kinase A (PKA) (AA 17-100) antibody
PKA 适用: 人, 小鼠 WB, IF (cc), IF (p), ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase A (PKA) (Catalytic Subunit) antibodyPKA 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- PKA (Protein Kinase A (PKA))
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别名
- PKAalpha/beta
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背景
- Rabbit Anti-PKAα/β cat Polyclonal Antibody,PRKACA, PKACA, cAMP-dependent protein kinase catalytic subunit alpha, PKA C-alpha, PRKACB, cAMP-dependent protein kinase catalytic subunit beta, PKA C-beta,PRKACA encodes one of the catalytic subunits of protein kinase A, which exists as a tetrameric holoenzyme with two regulatory subunits and two catalytic subunits, in its inactive form. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. cAMP-dependent phosphorylation of proteins by protein kinase A is important to many cellular processes, including differentiation, proliferation, and apoptosis. Constitutive activation of PRKACA caused either by somatic mutations, or genomic duplications of regions that include PRKACA, have been associated with hyperplasias and adenomas of the adrenal cortex and are linked to corticotropin-independent Cushing's syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. Tissue-specific isoforms that differ at the N-terminus have been described, and these isoforms may differ in the post-translational modifications that occur at the N-terminus of some isoforms.,cAMP-dependent protein kinase catalytic subunit alpha
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分子量
- observerd band 38kDa
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基因ID
- 5566, 5567
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途径
- SARS-CoV-2 Protein Interactome
抗原
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