PIAS3 抗体 (AA 10-90)
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Quick Overview for PIAS3 抗体 (AA 10-90) (ABIN7216554)
抗原
See all PIAS3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 10-90
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原理
- PIAS 3 Polyclonal Antibody
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特异性
- PIAS 3 Polyclonal Antibody detects endogenous levels of PIAS 3 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the N-terminal region of human PIAS 3 at AA range: 10-90
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))
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别名
- PIAS 3
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背景
- Rabbit Anti-PIAS 3 Polyclonal Antibody,PIAS3, E3 SUMO-protein ligase PIAS3, Protein inhibitor of activated STAT protein 3,PIAS3 encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. Protein inhibitor of activated STAT 3 functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of PIAS3 have been identified, but the full-length nature of some of these variants has not been determined.,E3 SUMO-protein ligase PIAS3
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分子量
- observerd band 68kDa
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基因ID
- 10401
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UniProt
- Q9Y6X2
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途径
- JAK/STAT Signaling
抗原
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