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PIAS3 抗体 (AA 10-90)

This 兔 多克隆 anti-PIAS3 antibody specifically detects PIAS3 in WB, ELISA 和 IHC (p). The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN7216554
发货至: 中国
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Quick Overview for PIAS3 抗体 (AA 10-90) (ABIN7216554)

抗原

See all PIAS3 抗体
PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))

适用

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人, 大鼠, 小鼠

宿主

  • 31
  • 3

克隆类型

  • 31
  • 2
多克隆

标记

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This PIAS3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 6
    • 5
    • 2
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    • 1
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    AA 10-90

    原理

    PIAS 3 Polyclonal Antibody

    特异性

    PIAS 3 Polyclonal Antibody detects endogenous levels of PIAS 3 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the N-terminal region of human PIAS 3 at AA range: 10-90

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))

    别名

    PIAS 3

    背景

    Rabbit Anti-PIAS 3 Polyclonal Antibody,PIAS3, E3 SUMO-protein ligase PIAS3, Protein inhibitor of activated STAT protein 3,PIAS3 encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. Protein inhibitor of activated STAT 3 functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of PIAS3 have been identified, but the full-length nature of some of these variants has not been determined.,E3 SUMO-protein ligase PIAS3

    分子量

    observerd band 68kDa

    基因ID

    10401

    UniProt

    Q9Y6X2

    途径

    JAK/STAT Signaling
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