POT1 抗体 (Internal Region)
Quick Overview for POT1 抗体 (Internal Region) (ABIN7216628)
抗原
See all POT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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原理
- POT1 Polyclonal Antibody
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特异性
- POT1 Polyclonal Antibody detects endogenous levels of POT1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human POT1
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- POT1 (Protection of Telomeres 1 (POT1))
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别名
- POT1
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背景
- Rabbit Anti-POT1 Polyclonal Antibody,POT1, Protection of telomeres protein 1, hPot1, POT1-like telomere end-binding protein,POT1 is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, protection of telomeres 1 functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of POT1 is associated with stomach carcinogenesis and its progression.,Protection of telomeres protein 1
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分子量
- observerd band 70kDa
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基因ID
- 25913
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UniProt
- Q9NUX5
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途径
- Cell Division Cycle, Telomere Maintenance
抗原
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