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PRCP 抗体

This anti-PRCP antibody is a 兔 多克隆 antibody detecting PRCP in WB 和 ELISA. Suitable for 人 和 小鼠.
产品编号 ABIN7230534
发货至: 中国

Quick Overview for PRCP 抗体 (ABIN7230534)

抗原

See all PRCP 抗体
PRCP (Prolylcarboxypeptidase (PRCP))

适用

  • 32
  • 17
  • 4
人, 小鼠

宿主

  • 45
  • 4
  • 2

克隆类型

  • 49
  • 2
多克隆

标记

  • 22
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PRCP antibody is un-conjugated

应用范围

  • 38
  • 19
  • 16
  • 13
  • 13
  • 5
  • 4
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA
  • 原理

    PCP Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of PCP protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human PCP protein

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    PRCP (Prolylcarboxypeptidase (PRCP))

    别名

    PCP

    背景

    Rabbit Anti-PCP Polyclonal Antibody,Lysosomal Pro-X carboxypeptidase, Angiotensinase C, Lysosomal carboxypeptidase C, Proline carboxypeptidase, Prolylcarboxypeptidase, PRCP,PRCP encodes a member of the peptidase S28 family of serine exopeptidases. Prolylcarboxypeptidase is proteolytically processed to generate the mature lysosomal prolylcarboxypeptidase. This enzyme cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH , but the enzyme activity is retained with some substrates at neutral pH . This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. A pseudogene of this gene has been identified on chromosome 2. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.,PCP

    分子量

    observerd band 54kDa

    基因ID

    5547

    UniProt

    P42785
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