PLOD2 抗体 (AA 600-680)
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Quick Overview for PLOD2 抗体 (AA 600-680) (ABIN7230696)
抗原
See all PLOD2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 600-680
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原理
- Rabbit Anti-PLOD2 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of PLOD2 protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human PLOD2 protein at AA range: 600-680
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- PLOD2 (Procollagen-Lysine 2-Oxoglutarate 5-Dioxygenase 2 (PLOD2))
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别名
- PLOD2
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背景
- Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2, Lysyl hydroxylase 2, LH2The protein encoded by PLOD2 is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of PLOD2 are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.
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分子量
- 81kD
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基因ID
- 5352
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UniProt
- O00469
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途径
- SARS-CoV-2 Protein Interactome
抗原
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