PRNP 抗体
Our Local Distributor
北京 101111
Quick Overview for PRNP 抗体 (ABIN7230778)
抗原
See all PRNP 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- PRIO Polyclonal Antibody
-
特异性
- The antibody detects endogenous levels of PRIO protein
-
纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
-
免疫原
- Synthesized peptide derived from part region of human PRIO protein
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
-
说明
-
Primary Antibody
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- PRNP (Prion Protein (PRNP))
-
别名
- PRIO
-
背景
- Rabbit Anti-PRIO Polyclonal Antibody,Major prion protein, PrP, ASCR, PrP27-30, PrP33-35C,Prion Protein, encoded by PRNP Gene, is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants.,PRIO
-
分子量
- observerd band 27kDa
-
基因ID
- 5621
-
UniProt
- P04156
-
途径
- Transition Metal Ion Homeostasis, Activated T Cell Proliferation
抗原
-