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PRNP 抗体

This 兔 多克隆 anti-PRNP antibody specifically detects PRNP in WB 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7230778
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PRNP 抗体 (ABIN7230778)

抗原

See all PRNP 抗体
PRNP (Prion Protein (PRNP))

适用

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  • 20
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  • 2
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  • 1
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人, 小鼠, 大鼠

宿主

  • 106
  • 31
  • 16
  • 2
  • 2
  • 1

克隆类型

  • 80
  • 78
多克隆

标记

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  • 2
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  • 2
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  • 2
This PRNP antibody is un-conjugated

应用范围

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  • 35
  • 27
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  • 19
  • 15
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  • 15
  • 9
  • 7
  • 3
  • 1
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Western Blotting (WB), ELISA
  • 原理

    PRIO Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of PRIO protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human PRIO protein

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    PRNP (Prion Protein (PRNP))

    别名

    PRIO

    背景

    Rabbit Anti-PRIO Polyclonal Antibody,Major prion protein, PrP, ASCR, PrP27-30, PrP33-35C,Prion Protein, encoded by PRNP Gene, is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants.,PRIO

    分子量

    observerd band 27kDa

    基因ID

    5621

    UniProt

    P04156

    途径

    Transition Metal Ion Homeostasis, Activated T Cell Proliferation
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