PZP 抗体 (AA 1301-1350)
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Quick Overview for PZP 抗体 (AA 1301-1350) (ABIN7230862)
抗原
See all PZP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1301-1350
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原理
- Rabbit Anti-PZP Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of PZP protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human PZP protein at AA range: 1301-1350
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- PZP (Pregnancy Zone Protein (PZP))
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别名
- PZP
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背景
- Pregnancy zone protein, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.
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分子量
- 163kD
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基因ID
- 5858
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UniProt
- P20742
抗原
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