KCNJ3 抗体 (pSer185)
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北京 101111
Quick Overview for KCNJ3 抗体 (pSer185) (ABIN7222000)
抗原
See all KCNJ3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer185
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原理
- KIR3.1 (phospho Ser185) Polyclonal Antibody
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特异性
- Phospho-KIR3.1 (S185) Polyclonal Antibody detects endogenous levels of KIR3.1 protein only when phosphorylated at S185.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human KIR3.1 Phospho-Ser185
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亚型
- IgG
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anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 3 (KCNJ3) (AA 279-501) antibody
KCNJ3 适用: 人, 小鼠, 猴 WB, IF, IHC, FACS, IHC (p) 宿主: 小鼠 Monoclonal 3E11 unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 3 (KCNJ3) (AA 81-180) antibodyKCNJ3 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 3 (KCNJ3) (Internal Region) antibodyKCNJ3 适用: 人, 小鼠, 大鼠 WB, IF, ELISA, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 3 (KCNJ3) (AA 350-487) antibodyKCNJ3 适用: 人 IF, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 3 (KCNJ3) (Center) antibodyKCNJ3 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 3 (KCNJ3) (AA 151-200), (pSer185) antibodyKCNJ3 适用: 人, 小鼠, 大鼠 WB, IF, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 3 (KCNJ3) (Internal Region) antibodyKCNJ3 适用: 人, 小鼠, 大鼠, 猴, Cow, 豚鼠, 马, Pig, Hamster IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 3 (KCNJ3) (Ser685) antibodyKCNJ3 适用: 人, 小鼠, 大鼠 WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 3 (KCNJ3) (AA 361-410) antibodyKCNJ3 适用: 人, 小鼠, 大鼠, 猴, Cow, 豚鼠, 马, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 3 (KCNJ3) (Extracellular) antibodyKCNJ3 适用: 人 WB, IF, IC, LCI 宿主: 小鼠 Monoclonal 3C3 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- KCNJ3 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 3 (KCNJ3))
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别名
- KIR3.1
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背景
- Rabbit Anti-KIR3.1 (phospho Ser185) Polyclonal Antibody,KCNJ3, GIRK1, G protein-activated inward rectifier potassium channel 1, GIRK-1, Inward rectifier K(+) channel Kir3.1, Potassium channel, inwardly rectifying subfamily J member 3,Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein KCNJ3, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and plays an important role in regulating heartbeat. It associates with three other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex that also couples to neurotransmitter receptors in the brain and whereby channel activation can inhibit action potential firing by hyperpolarizing the plasma membrane. These multimeric G-protein-gated inwardly-rectifying potassium (GIRK) channels may play a role in the pathophysiology of epilepsy, addiction, Down's syndrome, ataxia, and Parkinson's disease. Alternative splicing results in multiple transcript variants encoding distinct proteins.,G protein-activated inward rectifier potassium channel 1
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分子量
- observerd band 50kDa
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基因ID
- 3760
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UniProt
- P48549
抗原
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