KCNJ11 抗体 (pThr224)
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北京 101111
Quick Overview for KCNJ11 抗体 (pThr224) (ABIN7222010)
抗原
See all KCNJ11 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pThr224
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原理
- KIR6.2 (phospho Thr224) Polyclonal Antibody
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特异性
- Phospho-KIR6.2 (T224) Polyclonal Antibody detects endogenous levels of KIR6.2 protein only when phosphorylated at T224.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human KIR6.2 Phospho-Thr224
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亚型
- IgG
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anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11) (AA 372-385), (Intracellular) antibody
KO Validated KCNJ11 适用: 大鼠 WB, IHC, IF, FACS, IC, IP 宿主: 兔 Polyclonal unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11) (AA 172-390) antibodyKCNJ11 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11) (Internal Region) antibodyVerified KCNJ11 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11) (AA 301-390) antibodyKCNJ11 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11) (Center) antibodyKCNJ11 适用: 人, 小鼠, 大鼠, 兔, Cow, Pig WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11) (AA 190-239) antibodyKCNJ11 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11) (AA 372-385), (Intracellular) antibodyKCNJ11 适用: 大鼠 WB, IHC, IF 宿主: 豚鼠 Polyclonal unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11) (Ser688) antibodyKCNJ11 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11) (AA 1-30), (N-Term) antibodyKCNJ11 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB21238 unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11) (AA 6-35), (N-Term) antibodyKCNJ11 适用: 人, 小鼠 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- KCNJ11 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11))
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别名
- KIR6.2
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背景
- Rabbit Anti-KIR6.2 (phospho Thr224) Polyclonal Antibody,KCNJ11, ATP-sensitive inward rectifier potassium channel 11, IKATP, Inward rectifier K(+) channel Kir6.2, Potassium channel, inwardly rectifying subfamily J member 11,Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by KCNJ11 is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and is found associated with the sulfonylurea receptor SUR. Mutations in this gene are a cause of familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), an autosomal recessive disorder characterized by unregulated insulin secretion. Defects in this gene may also contribute to autosomal dominant non-insulin-dependent diabetes mellitus type II (NIDDM), transient neonatal diabetes mellitus type 3 (TNDM3), and permanent neonatal diabetes mellitus (PNDM). Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.,ATP-sensitive inward rectifier potassium channel 11
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分子量
- observerd band 40kDa
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基因ID
- 3767
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UniProt
- Q14654
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途径
- Negative Regulation of Hormone Secretion
抗原
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