POLR2C 抗体
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北京 101111
Quick Overview for POLR2C 抗体 (ABIN7231148)
抗原
See all POLR2C 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit Anti-RPB3 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of RPB3 protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human RPB3 protein
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- POLR2C (Polymerase (RNA) II (DNA Directed) Polypeptide C, 33kDa (POLR2C))
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别名
- RPB3
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背景
- DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II 33 kDa polypeptide, DNA-directed RNA polymerase II subunit C, RPB31POLR2C encodes the third largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a cysteine rich region and exists as a heterodimer with another polymerase subunit, POLR2J. These two subunits form a core subassembly unit of the polymerase. A pseudogene has been identified on chromosome 21. POLR2C (RNA Polymerase II Subunit C) is a Protein Coding gene. Diseases associated with POLR2C include Hiv-1. Among its related pathways are Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 and DNA damage_Role of Brca1 and Brca2 in DNA repair.
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分子量
- 30kD
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基因ID
- 5432
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UniProt
- P19387
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途径
- Regulatory RNA Pathways
抗原
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