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PCGF2 抗体

This anti-PCGF2 antibody is a 兔 多克隆 antibody detecting PCGF2 in WB 和 ELISA. Suitable for 人 和 小鼠.
产品编号 ABIN7230524
发货至: 中国

Quick Overview for PCGF2 抗体 (ABIN7230524)

抗原

See all PCGF2 抗体
PCGF2 (Polycomb Group Ring Finger 2 (PCGF2))

适用

  • 36
  • 17
  • 15
人, 小鼠

宿主

  • 33
  • 2
  • 1

克隆类型

  • 34
  • 2
多克隆

标记

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  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This PCGF2 antibody is un-conjugated

应用范围

  • 31
  • 15
  • 13
  • 3
  • 1
  • 1
Western Blotting (WB), ELISA
  • 原理

    PCGF2 Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of PCGF2 protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human PCGF2 protein

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    PCGF2 (Polycomb Group Ring Finger 2 (PCGF2))

    别名

    PCGF2

    背景

    Rabbit Anti-PCGF2 Polyclonal Antibody,Polycomb group RING finger protein 2, DNA-binding protein Mel-18, RING finger protein 110, Zinc finger protein 144,The protein encoded by PCGF2 gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in embryogenesis, cell cycles and tumorigenesis. This protein was shown to act as a negative regulator of transcription and has tumor suppressor activity. The expression of this gene was detected in various tumor cells, but is limited in neural organs in normal tissues. Knockout studies in mice suggested that this protein may negatively regulate the expression of different cytokines, chemokines, and chemokine receptors, and thus plays an important role in lymphocyte differentiation and migration, as well as in immune responses.,PCGF2

    分子量

    observerd band 37kDa

    基因ID

    7703

    UniProt

    P35227

    途径

    Chromatin Binding
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