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PAOX 抗体 (AA 260-340)

This 兔 多克隆 anti-PAOX antibody specifically detects PAOX in WB, ELISA 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7217746
发货至: 中国
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Quick Overview for PAOX 抗体 (AA 260-340) (ABIN7217746)

抗原

See all PAOX 抗体
PAOX (Polyamine Oxidase (Exo-N4-Amino) (PAOX))

适用

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宿主

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克隆类型

  • 27
多克隆

标记

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This PAOX antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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    AA 260-340

    原理

    PAOX Polyclonal Antibody

    特异性

    PAOX Polyclonal Antibody detects endogenous levels of PAOX protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human PAOX at AA range: 260-340

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    PAOX (Polyamine Oxidase (Exo-N4-Amino) (PAOX))

    别名

    PAOX

    背景

    Rabbit Anti-PAOX Polyclonal Antibody,PAOX, PAO, Peroxisomal N(1)-acetyl-spermine/spermidine oxidase, Polyamine oxidase,PAOX (Polyamine Oxidase (Exo-N4-Amino)) is a Protein Coding gene. Among its related pathways are Metabolism and cytochrome P450. Gene Ontology (GO) annotations related to this gene include receptor binding and polyamine oxidase activity. An important paralog of this gene is KDM1B. Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: n(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs.,Peroxisomal N(1)-acetyl-spermine

    分子量

    observerd band 70kDa

    基因ID

    196743

    UniProt

    Q6QHF9
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