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PCBP2 抗体 (AA 30-110)

The 兔 多克隆 anti-PCBP2 antibody is suitable to detect PCBP2 in samples from 人 和 小鼠. It has been validated for WB 和 ELISA.
产品编号 ABIN7230518
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PCBP2 抗体 (AA 30-110) (ABIN7230518)

抗原

See all PCBP2 抗体
PCBP2 (Poly(rC) Binding Protein 2 (PCBP2))

适用

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人, 小鼠

宿主

  • 50
  • 5

克隆类型

  • 36
  • 19
多克隆

标记

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This PCBP2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 30-110

    原理

    PCBP2 Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of PCBP2 protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human PCBP2 protein at AA range: 30-110

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    PCBP2 (Poly(rC) Binding Protein 2 (PCBP2))

    别名

    PCBP2

    背景

    Rabbit Anti-PCBP2 Polyclonal Antibody,Poly(rC)-binding protein 2, Alpha-CP2, Heterogeneous nuclear ribonucleoprotein E2, hnRNP E2,PCBP2 (Poly(RC) Binding Protein 2) is a Protein Coding gene. Among its related pathways are Translational Control and mRNA Splicing - Major Pathway. The protein encoded by PCBP2 appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2. PCBP2 and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. PCBP2 also has two processed pseudogenes (PCBP2P1 and PCBP2P2). Multiple transcript variants encoding different isoforms have been found for PCBP2.,PCBP2

    分子量

    observerd band 40kDa

    基因ID

    5094

    UniProt

    Q15366
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