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Poly(A) Binding Protein, Cytoplasmic, Pseudogene 2 (PABPCP2) (AA 170-250) 抗体

This 兔 多克隆 anti-not_set antibody specifically detects not_set in WB 和 ELISA. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7230470
发货至: 中国
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Quick Overview for Poly(A) Binding Protein, Cytoplasmic, Pseudogene 2 (PABPCP2) (AA 170-250) 抗体 (ABIN7230470)

抗原

See all Poly(A) Binding Protein, Cytoplasmic, Pseudogene 2 (PABPCP2) 抗体
Poly(A) Binding Protein, Cytoplasmic, Pseudogene 2 (PABPCP2)

适用

人, 小鼠

宿主

  • 1
  • 1

克隆类型

  • 2
多克隆

标记

  • 2
非结合性

应用范围

Western Blotting (WB), ELISA
  • 抗原表位

    • 1
    • 1
    AA 170-250

    原理

    PABP2 Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of PABP2 protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human PABP2 protein at AA range: 170-250

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    Poly(A) Binding Protein, Cytoplasmic, Pseudogene 2 (PABPCP2)

    别名

    PABP2

    背景

    Rabbit Anti-PABP2 Polyclonal Antibody,Polyadenylate-binding protein 2, PABP-2, Poly(A)-binding protein 2, Nuclear poly(A)-binding protein 1, Poly(A)-binding protein II, PABII, Polyadenylate-binding nuclear protein 1,PABPN1 (Poly(A) Binding Protein Nuclear 1) encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. PABPN1 contains a GCG trinucleotide repeat at the 5' end of the coding region, and expansion of this repeat from the normal 6 copies to 8-13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Related pseudogenes have been identified on chromosomes 19 and X. Read-through transcription also exists between this gene and the neighboring upstream BCL2-like 2 (BCL2L2) gene.,PABP2

    分子量

    observerd band 33kDa

    基因ID

    8106

    UniProt

    Q86U42
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