PABP 抗体
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北京 101111
Quick Overview for PABP 抗体 (ABIN7230468)
抗原
See all PABP (PABPC1) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- PABP1 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of PABP1 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human PABP1 protein
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亚型
- IgG
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anti-Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1) (AA 350-450) antibody
PABPC1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1) antibodyPABPC1 适用: 人, 兔, 小鸡, 非洲爪蟾, Hamster WB, ELISA, IF, IP, FACS, ICC 宿主: 小鼠 Monoclonal 10E10 unconjugated
anti-Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1) (meArg455), (meArg460) antibodyPABPC1 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1) (AA 1-636) antibodyPABPC1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1) (AA 101-200) antibodyPABPC1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1) (AA 431-480) antibodyPABPC1 适用: 人, 小鼠, 大鼠, 兔, 小鸡, Cow, 犬, 豚鼠, 马, 绵羊, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1) (AA 250-279) antibodyPABPC1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB20873 unconjugated
anti-Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1) (Middle Region) antibodyPABPC1 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 豚鼠, 马, 绵羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- PABP (PABPC1) (Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1))
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别名
- PABP1
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背景
- Rabbit Anti-PABP1 Polyclonal Antibody,Polyadenylate-binding protein 1, PABP-1, Poly(A)-binding protein 1,Binds the poly(A) tail of mRNA, including that of its own transcript. May be involved in cytoplasmic regulatory processes of mRNA metabolism such as pre-mRNA splicing. Its function in translational initiation regulation can either be enhanced by PAIP1 or repressed by PAIP2. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo. Involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. Involved in regulation of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons, for the recognition of premature termination codons (PTC) and initiation of NMD a competitive interaction between UPF1 and PABPC1 with the ribosome-bound release factors is proposed. By binding to long poly(A) tails, may protect them from uridylation by ZCCHC6/ZCCHC11 and hence contribute to mRNA stability (PubMed: 25480299). Positively regulates the replication of dengue virus (DENV) (PubMed: 26735137).,PABP1
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分子量
- observerd band 69kDa
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基因ID
- 26986
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UniProt
- P11940
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途径
- SARS-CoV-2 Protein Interactome
抗原
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