PLK3 抗体 (AA 200-280)
Quick Overview for PLK3 抗体 (AA 200-280) (ABIN7214922)
抗原
See all PLK3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 200-280
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原理
- Fnk Polyclonal Antibody
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特异性
- Fnk Polyclonal Antibody detects endogenous levels of Fnk protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human Fnk at AA range: 200-280
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- PLK3 (Polo-Like Kinase 3 (PLK3))
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别名
- Fnk
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背景
- Rabbit Anti-Fnk Polyclonal Antibody,PLK3, CNK, FNK, PRK, Serine/threonine-protein kinase PLK3, Cytokine-inducible serine/threonine-protein kinase, FGF-inducible kinase, Polo-like kinase 3, PLK-3, Proliferation-related kinase,Serine/threonine-protein kinase PLK3 encoded by PLK3 is a member of the highly conserved polo-like kinase family of serine/threonine kinases. Members of this family are characterized by an amino-terminal kinase domain and a carboxy-terminal bipartite polo box domain that functions as a substrate-binding motif and a cellular localization signal. Polo-like kinases are important regulators of cell cycle progression. This gene has also been implicated in stress responses and double-strand break repair. In human cell lines, this protein is reported to associate with centrosomes in a microtubule-dependent manner, and during mitosis, the protein becomes localized to the mitotic apparatus. Expression of a kinase-defective mutant results in abnormal cell morphology caused by changes in microtubule dynamics and mitotic arrest followed by apoptosis.,serine threonine-protein kinase PLK3
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分子量
- observerd band 70kDa
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基因ID
- 1263
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UniProt
- Q9H4B4
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途径
- Regulation of long-term Neuronal Synaptic Plasticity
抗原
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