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PLA2G4A 抗体 (pSer505)

This 兔 多克隆 anti-PLA2G4A antibody specifically detects PLA2G4A in WB, ELISA, IF 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7223166
发货至: 中国
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Quick Overview for PLA2G4A 抗体 (pSer505) (ABIN7223166)

抗原

See all PLA2G4A 抗体
PLA2G4A (Phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) (PLA2G4A))

适用

  • 71
  • 46
  • 15
  • 3
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 78
  • 8
  • 2
  • 1

克隆类型

  • 73
  • 16
多克隆

标记

  • 47
  • 8
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PLA2G4A antibody is un-conjugated

应用范围

  • 74
  • 44
  • 23
  • 23
  • 19
  • 14
  • 14
  • 12
  • 11
  • 4
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 28
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer505

    原理

    cPLA2 (phospho Ser505) Polyclonal Antibody

    特异性

    Phospho-cPLA2 (S505) Polyclonal Antibody detects endogenous levels of cPLA2 protein only when phosphorylated at S505.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human cPLA2 Phospho-Ser505

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    PLA2G4A (Phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) (PLA2G4A))

    别名

    cPLA2

    背景

    Rabbit Anti-cPLA2 (phospho Ser505) Polyclonal Antibody,PLA2G4A, CPLA2, PLA2G4, Cytosolic phospholipase A2, cPLA2, Phospholipase A2 group IVA,PLA2G4A (phospholipase A2 group IVA) encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles. Alternative splicing results in multiple transcript variants.,Cytosolic phospholipase A2

    分子量

    observerd band 110kDa

    基因ID

    5321

    UniProt

    P47712

    途径

    Inositol Metabolic Process, G-protein mediated Events, VEGF Signaling
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